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inTEST Corporation lrg biomarker
Lrg Biomarker, supplied by inTEST Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lrg+biomarker/lrg+biomarker/pm39155217-23-0-17
Average 90 stars, based on 1 article reviews
lrg biomarker - by Bioz Stars, 2026-09
90/100 stars

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Biomarker Discovery:

Article Title: Early change in serum leucine-rich α-2-glycoprotein predicts clinical and endoscopic response in ulcerative colitis.
Article Snippet: ROC analysis showed that LRG the had numerically highest AUC (0.82) for predicting subsequent endoscopic improvement (Fig. 7D-F) with a cutoff of 19.7 (sensitiv- Intest Res, Published online 7www.irjournal.org ity 0.77, specificity 0.71, respectively).

Article Title: Efficacy of serum leucine-rich alpha-2 glycoprotein in predicting findings of Crohn's disease small bowel lesion in capsule endoscopy.
Article Snippet: Cutoff: 85, AUC: 0.68 CDAI 1-Specificity 1.0 0.9 0.8 0.7 0.6 0.5 0.4 0.3 0.2 0.1 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1.0 Se ns iti vi ty Cutoff: 14 μg/mL, AUC: 0.92 LRG 1.0 0.9 0.8 0.7 0.6 0.5 0.4 0.3 0.2 0.1 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1.0 Se ns iti vi ty Cutoff: 0.14 mg/dL, AUC: 0.70 CRP 1-Specificity 1.0 0.9 0.8 0.7 0.6 0.5 0.4 0.3 0.2 0.1 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1.0 Se ns iti vi ty Intest Res, Published online 5www.irjournal.org of LRG was 14 μg/mL, the presence of SB ulcer ≥ 0.5 cm could be discriminated with a sensitivity of 92.3%, specificity of 81.5%, PPV of 70.6%, NPV of 95.7%, +LR of 4.985, –LR of 0.094, and accuracy of 85.0% (Table 2).

Article Title: Early change in serum leucine-rich α-2-glycoprotein predicts clinical and endoscopic response in ulcerative colitis.
Article Snippet: Conclusions: LRG can be an early-phase biomarker predicting subsequent clinical and endoscopic response to induction therapy. (Intest Res, Published online ) Key Words: Leucine-rich α-2-glycoprotein; Inflammatory bowel disease; Ulcerative colitis; Biomarkers Received September 27, 2023.

Article Title: Combination of leucine-rich alpha-2 glycoprotein and fecal markers detect Crohn's disease activity confirmed by balloon-assisted enteroscopy.
Article Snippet: Conclusions: The biomarkers LRG, fecal calprotectin, and fecal hemoglobin can serve as noninvasive and accurate tools for assessing activity in CD patients confirmed by BAE, especially when used in combination. (Intest Res, Published online ) Key Words: Crohn disease; Leucine-rich alpha2-glycoprotein, human; Leukocyte L1 antigen complex; Biomarkers; Inflammatory bowel diseases Received August 1, 2023.

Article Title: Leucine-rich alpha-2 glycoprotein is useful in predicting clinical relapse in patients with Crohn's disease during biological remission.
Article Snippet: LRG is a useful biomarker for predicting prognosis, even in patients with intestinal stenosis, or previous/present fistulas. (Intest Res, Published online ) Key Words: Crohn disease; Leucine-rich alpha-2 glycoprotein; Biomarkers Received March 15, 2024.

Article Title: Early change in serum leucine-rich α-2-glycoprotein predicts clinical and endoscopic response in ulcerative colitis.
Article Snippet: At week 1, LRG and CRP were significantly lower in the remission group (LRG, 20.6 μg/mL vs. 28.4 μg/mL, P < 0.001; CRP, 50 40 30 20 10 0 Baseline Week 1 Week 8 P=0.223 P<0.001 P<0.001A Remission Non-remission LR G (μ g/ m L) 5,000 4,000 3,000 2,000 1,000 0 Baseline Week 1 Week 8 P=0.058 P=0.227 P=0.007C Remission Non-remission FC (m g/ kg ) Intest Res, Published online 5www.irjournal.org 0.9 mg/dL vs. 2.3 mg/dL, P < 0.001), while FC showed no significant difference (1,838 mg/kg vs. 2,856 mg/kg, P = 0.277).



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